Package 'lddesign' Title Design of Experiments for Detection of Linkage Disequilibrium
نویسنده
چکیده
Description R package for design of experiments for association studies for detection of linkage disequilibrium. Uses an existing deterministic power calculation for detection of linkage disequilibrium between a bi-allelic QTL and a bi-allelic marker, together with the Spiegelhalter and Smith Bayes factor to generate designs with power to detect effects with a given Bayes factor.
منابع مشابه
The Pattern of Linkage Disequilibrium in Livestock Genome
Linkage disequilibrium (LD) is bases of genomic selection, genomic marker imputation, marker assisted selection (MAS), quantitative trait loci (QTL) mapping, parentage testing and whole genome association studies. The Particular alleles at closed loci have a tendency to be co-inherited. In linked loci this pattern leads to association between alleles in population which is known as LD. Two metr...
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